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C1-27, but not LCS3, prevented binding of CMFDA, implying that LCS3 does not occupy the GSTO1 active site and is thus unlikely to be an inhibitor of the enzyme (Supplementary Fig

10.3389/fnins.2014.00182 [DOI] [PMC free article] [PubMed] [Google Scholar] Braun S

Incorporation of polyunsaturated fatty acids into phospholipids, the major component of cell membranes, represents a conserved vulnerability that necessitates complex antioxidative defense system

In conclusion, canine tumor cells with low proteasome activity are radio-resistant due to high GSH content and low ROS accumulation

Samaan Z, Gaysina D, Cohen-Woods S, Craddock N, Jones L, Korszun A, Owen M, Mente A, McGuffin P, Farmer A (2011) Methylenetetrahydrofolate reductase gene variant ( MTHFR C677T) and migraine: a case control study and meta-analysis