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The labels have now been corrected to Con-DSS, Si-DSS, Con and Si (from left to right)

Consequently, the elevation of pro-inflammatory cytokines IL-1 and TNF- in bronchoalveolar lavage fluid (BALF), as well as neutrophil recruitment, pulmonary edema and alveolar wall thickening caused by LPS was blocked by ISA (Yuan et al., 2018)

Zamani et al., 2022

While such optimizations to trial design may succeed in gaining approval for additional immunosuppressive therapies, allowing pharmaceutical companies to claim their share of the insurance market, they do nothing to genuinely benefit patients with UC and instead contribute to escalating healthcare costs