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It attenuates inflammatory signaling pathways by inhibiting the HMGB1/NF-B cascade and reducing the levels of pro-inflammatory cytokines such as TNF-, IL-6, and IL-1

[Abstract]2021 Sep 28;15(9):14709-14724

Overexpression of IDH2 decreases ROS levels and increases cancer cell growth

87 In addition, as shown in a recent study on allosteric communications in antibodyantigen recognition and FcR activation, 97 more effective IC constructs may be generated