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Additionally, quercetin can upregulate pyroptosis-related genes (GSDMD, GSDME, cleaved CASP1, NLRP3) and activate the pyroptosis pathway to suppress cell proliferation (85)

However, it was not recognized at the time that evidence for the protein binding hypothesis was obtained in animals on a normal diet whereas the LPO hypothesis was derived from animals fed a vitamin E-deficient diet high in polyunsaturated fatty acids (PUFAs), i.e., in animals highly susceptibility to LPO [61]

Elongation Factor Tu Mutants Expand Amino Acid Tolerance of Protein Biosynthesis System

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In the skin, vitamin C plays a critical role in synthesizing collagen, the protein that provides structure and elasticity