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These mechanisms include enhanced metabolic activity of drug-detoxifying proteins such as glutathione-S-transferase, increased efflux of the drug partially caused by upregulation of ATP-binding cassette (ABC) transporters, changes in microtubule formation and kinetics due to overexpression of III-tubulin, and mutations in tumor suppressor genes [101]

Strengthens Skins Defense : Glutathione fortifies the skins natural barrier, improving hydration and resilience

2008 Nov;38(10):1976

8 One proposed mechanism underlying this phenomenon is the competitive utilization of CYP 2E1 in herbal drug metabolism that would decrease APAPs conversion into its toxic metabolites, such as NAPQI

Perhaps the mechanism that sigma1 receptor agonists can prevent virus replication might also work, but the group who used a sigma1 receptor antagonist was too small to compare it with the big group who used an sigma1 agonist and we got only anecdotal evidence for it