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Rather, this aggregation is an essential step that promotes the interaction of cargo with sorting receptors (e.g., CPE and sortilin) at the TGN membrane [51]

A ferroptosis-induced rat model was established by intraperitoneal injection of Erastin (GC16630-50mg, GLPBIO, USA), randomly assigning rats to Sham ( n = 8) and Erastin ( n = 9) groups