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The protective effects of ALCAR reported may occur by several mechanisms, including a general anti-inflammatory effect, activation of the Nrf2/antioxidant response, or support of oxidative metabolism by providing acetyl moieties to the TCA cycle, thereby bypassing the enzyme pyruvate dehydrogenase that is vulnerable to oxidative damage [31]

doi: 10.7759/cureus.14815

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Again, talk with your doctor or get the test done yourself so that you have a baseline to know if the interventions are working for you

In sporadic AD, astrocytic overexpression of the glycolytic enzyme HK1 markedly normalizes most metabolic abnormalities and improves cognitive performance, highlighting HK1 as a potential therapeutic target