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Therefore, we hypothesize that in energy production, a compensatory increase in ATP production from glycolysis combined with mitochondrial oxidative phosphorylation could maintain overall ATP levels in mild preeclampsia, and that in terms of substance synthesis, the substances that need to maintain the normal function of the placenta can be ensured, thanks to the compensatory production of acetyl-CoA

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Transl Psychiatry 13(1):106 Buchanan JL, Rauckhorst AJ, Taylor EB (2023) 3-hydroxykynurenine is a ROS-inducing cytotoxic tryptophan metabolite that disrupts the TCA cycle