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Vawter MP, Dillon-Carter O, Tourtellotte WW, Carvey P, Freed WJ

In addition, many important issues need to be further explored, such as the mechanism of the superimposed effect and its safety when polyphenols are applied in combination, the possible interactions with other chemotherapeutic agents such as 5 - fluorouracil, paclitaxel analogs, gemcitabine, pemetrexed, etc., as well as whether oral polyphenols have an impact on ototoxicity by regulating the intestinal flora

It creates an environment where we have legalized snake oil, says Pieter Cohen, an internal medicine physician at Cambridge Health Alliance in Massachusetts who studies supplement safety

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Regulatory enzymes of lactylation The lactylation modification process involves specific regulatory enzymes, including writers, readers, and erasers, that are responsible for the addition, recognition, or removal of the lactyl moiety, respectively