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5 Using elevated metabolite levels (ie, serum methylmalonic acid [MMA] or homocysteine [Hcy]) to define deficiency, the screening serum B 12 cutoff used in many diagnostic algorithms has been raised to 250 pg/mL to 300 pg/mL to provide greater sensitivity

Journal of Bacteriology, 185 (16), 4948-4955

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For instance, while 5-Amino-1MQ targets NAMPT in adipose tissue, another compound might enhance mitochondrial biogenesis, or perhaps regulate appetite through different mechanisms

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