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3) How soon will I feel a difference

Symptoms include bone pain, muscle weakness, frequent colds, low energy, and mood disorders like depression and anxiety

In SURPASS-2, the rates of all reported GI side effectsincluding nausea, diarrhoea, vomiting, dyspepsia, decreased appetite, constipation and abdominal painoccurring with tirzepatide (4044.9%) were generally comparable to those seen with semaglutide (41.2%) [9]

This makes it particularly valuable for comparative studies examining synergistic hormone regulation and for research requiring robust, physiologically-appropriate GH elevation

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