glutathione synthesis in body Figure 2 from A mouse model to study

Lab testing cannot diagnose oxidative stress as the cause of heart disease, and no single antioxidant marker can determine whether a person will experience a heart attack or stroke

In conclusion, effective treatment is dependent on proper diagnosis

It is important to note that curcumin exhibits a biphasic dose-response relationship: lower doses activate protective pathwaysincluding increased total glutathione (GSx) and GST activitywhile higher doses deplete GSH, reduce related metabolites (e.g., taurine, homocysteine), and may induce pro-oxidant effects or cellular toxicity (Scharstuhl et al., 2009)

Cell 19, 1526 [DOI] [PubMed] [Google Scholar] 59.Bar-Peled L., Schweitzer L.D., Zoncu R

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