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[] While therapeutic ozone has demonstrated efficacy in ischemic stroke, diabetic ulcers, and immune-mediated disorders, [] its application in preeclamptic pregnancy remains virtually uncharted in mainstream reproductive medicine

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The level of NADPH in cells was detected by NADPH oxidase activity reagent box

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Nevertheless, emerging data allow us to propose that severe hyperhomocysteinemia might primarily have homocysteinylation effects related to homocysteine and/or its by-products (as homocysteine thiolactone) that would affect the vascular wall structure through a mechanism independent of an oxidant stress