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Animal models, while more physiologically complex, are expensive, ethically constrained, and often poorly predictive of human pathophysiology, contributing to translational failure (56)

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Indeed, cluster MES-2 shares 17% of marker genes with MES-1, and 37% of genes with the cluster of mature myocytes (MYO-2, described below), providing additional support to the idea that there are cells with dual identities in both MES-2

Clinical evaluation Body mass was measured daily at 8 am on a balance-beam scale with subjects wearing light clothing and no shoes

Individuals who have small LDL may have normal or low LDL-C but may have many LDL particles in circulation