Thalidomide-5'-O-C4-OH deuterium-labeled-bronic ester a novel and potent GSPT1

a novel and potent GSPT1 degrader displaying selectivity over 9000 proteins

03 SMILES C[C@H]1CN(C[C@@H](C)C1(F)F)C1=NC(NC2=CC3=C(C=C2)N(C)C(=O)N3CCC(C)(C)C)=C(Cl)C=N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

org DOI: 10

NCCOCCN1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

304 SMILES BrCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Thalidomide-5'-O-C4-OH deuterium-labeled-bronic ester a novel and potent GSPT1Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Thalidomide 5' O C4 OH Synonyms CAS Number n a Related CAS Molecular Formula C17H18N2O6 Molecular Weight 346. 339 SMILES OCCCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature