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A recent meta-analysis showed a considerable inconsistency among the findings obtained by 74 original PD-focused metabolomics studies, potentially attributable to the different biospecimens analyzed, antiparkinsonian drugs-related effects, different disease stages, genetic background, ethnicity, diet, exercise level, and analytical platform employed 13

Increased stress susceptibility and impaired differentiation of astrocytes and neurons was found in co-cultures and in neural organoids generated from AxD patient-derived induced pluripotent stem cells with AxD-causing GFAP R239C mutation 334

Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation

Subcellular distribution of glutathione and its dynamic changes under oxidative stress in the yeast Saccharomyces cerevisiae

Experiences and translatability of in vitro and in vivo models to evaluate caprate as a permeation enhancer