kb glutathione review 2018 Frontiers Frontiers | Pathogen-induced mitochondrial dysfunction:

NAD+ helps to make NADPH, which is the energy that keeps Glutathione active

Causal associations between serum bilirubin levels and decreased stroke risk: A two-sample Mendelian randomization study

L.PerazzioS

When NRX is oxidized by NADPH oxidase 1 (NOX1)-derived H2O2 or lipid peroxide (ROOH), DVL is released and inhibits glycogen synthesis kinase 3 (GSK3) in the -catenin degradation complex, thereby stabilizing the -catenin in the cytoplasm and partially entering the nucleus to activate the target gene GPX2 by correlation with the TCF/LEF transcription factor family (Figure 2)

This review suggests the further replication of these studies to confirm the therapeutic capability of these phytochemicals in providing uroprotective effects