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Recurrent spontaneous seizure activity in hippocampal neuronal networks in culture

Saraswathi et al 265 indicated that hematopoietic COX-1 deletion in mice significantly reduced TXB2 (thromboxane B2) level with increased adipose tissue inflammation and impaired metabolic homeostasis, suggesting an essential role of COX-1 and its metabolite TXB2 in maintaining energy homeostasis