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Direct determination of faecal wet weight by lyophilisation was considered inappropriate because this underestimates relative faecal wet weight due to evaporation of water from the faecal pellets in the collection vessels of the metabolic cages

After inhalation of the solution by patients with COPD, urinary excretion is 18.6% (0.932 mcg) of the dose, the remainder being mainly non-absorbed drug in the gut that is eliminated via the feces

Healthcare practitioners might soon create custom protocols based on each person's redox profile to match their unique metabolic needs

doi: 10.3760/cma.j.issn.0376-2491.2016.33.013 18 ChenM.HuangQ.XuW.SheC.XieZ

Our finding that there is only a small increase increase in covalent binding after a therapeutic dose, even with a four-fold increase in CYP P-450 activity supports this idea