griffith wo 1980 determination of glutathione Dynamic responses the system to acute oxidative stress in dystrophic mouse (mdx) muscles | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology Measurement of Oxidized/Reduced Glutathione Ratio

The ensuing GSH depletion indirectly inactivates GPx4

Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor

doi: 10.1016/s0167-4781(00)00276-1

Research shows that both moderate-intensity continuous training (MICT, 50%70% VO 2 max) and high-intensity interval training (HIIT, 85%95% VO 2 max) can effectively activate the Nrf2 pathway, with HIIT being 30%40% more effective in upregulating antioxidant enzymes than MICT (Martinez-Canton et al., 2024)

Tumor-targeted glutathione oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma