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Concomitantly, previous and our data suggest that the promiscuous Opp oligopeptide transporter is an ubiquitous GSH import system, however, whether or not Opp in other organisms imports oxidized glutathione needs to be elucidated

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In the brain of a mouse, the over-expression of -catenin levels mimics the anti-depressant-like effects of lithium 86 , while the knockout of -catenin leads to a depression-like phenotype 87,88