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Lo, M., Ling, V., Wang, Y

The process of drug development involves not only technical challenges but also the need for pharmaceutical companies to engage in early communication with regulatory authorities

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Other cascade reactions activated downstream, such as phagosome biogenesis, endosomal trafficking, autophagy, or secretion of soluble factors can be benefic or detrimental for the pathogen or the macrophage (Stamm et al., 2015)