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It was also approved in combination with Merck's Keytruda (pembrolizumab) or Keytruda Qlex (pembrolizumab and berahyaluronidase alfa-pmph) for the first-line treatment of adults with unresectable locally advanced or metastatic TNBC whose tumors express PD-L1 (CPS 10) as determined by an FDA-authorized test

Itraconazole and fluconazole-induced toxicity in rat hepatocytes: a comparative in vitro study

For further studies we suggest to involve complexes 1 and 3 , possessing strongly bound ligands, as suitable model complexes both biologically relevant oxidation states +II and +III, with good solubility in water and biological media

The circulating blood flow through the liver becomes severely impaired as the remaining liver cells cannot get enough oxygen and nutrients

4.5 Metal-organic frameworks The investigators have found that enzyme-integrated metal-organic frameworks (MOFs) had antioxidant activity and chiral-dependent BBB trans endocytosis