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Overexpression of NDI1 in HCT116 was achieved by transfecting 1 10 6 cells with plasmid PXMS-NDI1 DNA (PMXS-NDI1 was a gift from D

doi: 10.1016/j.omto.2021.12.006 328 ZhaoDLiuNShiKWangXWuG

Cebraian J1, Messeguer A, Facino RM, Garcia Anton JM

doi: 10.3390/nu12020351 350 XuC.SuoY.WangX.QinJ

If the agent successfully passes initial human safety evaluations, it advances to Phase 2 trials, which assess clinical efficacy and optimal dosing in a small sample of patients afflicted with the target condition