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A novel non-opioid protocol for medically supervised opioid withdrawal and transition to antagonist treatment

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Using mouse models of head and neck cancer, we show that BSC gal augments the radiodynamic and immunotherapeutic effects of SABR at the primary and metastatic tumors by promoting tumor-inhibitory leukocytes, upregulating cytotoxic granzyme B and reducing immunosuppressive cell populations

As previous studies demonstrated that a daily dose of 20 mg kg 1 of MDMG-935P for only 5 days effectively reduced oxalate in primary hyperoxaluric mice 54 , we chose to administer up to 10 mg kg 1 d 1 to account for the long duration of the treatments