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This suggests a high effectiveness and significant selectivity of FOXO4-DRI towards senescent cells [127]

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50 percent of copper is stored in the gallbladder as bile, while the remaining is loosely bound to albumin and other small molecules and excreted into the stomach.55 Excess consumption of copper-rich foods (such as animal products) can lead to liver damage and cause excess free copper ions into the circulation.58 Figure 8: Excess free copper ions in the circulation can damage the structure, function, and genetic code of various organs, decrease red blood cell production, and alter skin pigmentation 56,57,58