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Breast Cancer (2018) 25(4):392401

Torres M, et al

WADA Technical Document - Minimum Required Performance Levels of Non-Threshold Substances

This includes the dynamic interplay between host immune responses and bacterial evasion, the genetic mutations that confer classical drug resistance, the epigenetic regulation in bacterial persistence and adaptive changes in bacterial cell wall architecture and core metabolism

Not only is the oocyte ultrastructure directly affected by the microenvironment created by the cancerous cells, but the cumulus cells can also show dysregulations, leading to a decreased oocyte competency