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-22.5% Avg body weight loss at highest dose (SURMOUNT-1) 96% Lost at least 5% body weight 72 weeks Trial duration Context: Clinical trial participants also received lifestyle intervention (diet and exercise counseling)

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Four models were established based on Cox regression: Model 1 and Model 3 were adjusted for age, type of fracture, hypertension, Hb, CCI score, sex, time from injury to surgery, and ALB, while Model 2 and Model 4 were fully adjusted