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NAC-loaded PLGA nanoparticles administered via nasal inhalation demonstrated increased deposition and better targeted delivery toward the lung (Puri et al., 2022)

Another approach to generate transgenic AIH animal models is the expression of antigens under the control of liver-specific promoters: since this approach is not capable of inducing liver damage on its own in the liver, a tolerogenic organ, it has to be coupled with adjuvants and/or adoptive transfer of antigen-specific T cells

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Management: Limit or avoid alcohol consumption during treatment