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Importantly, the dependency on riboflavin and subsequently impaired oxidative phosphorylation upon perturbation of riboflavin metabolism can be exploited by sensitizing AMLs to the BCL-2 inhibitor venetoclax

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Oral administration of 2 g of vitamin C in healthy populations helped to reduce aggregation platelet and arterial stiffness, however, the exact mechanism has not been fully explored (Wilkinson et al

Extended-interval dosing is associated with equivalent efficacy and reduced nephrotoxicity, with a non-significant trend toward lower ototoxicity in pooled analyses

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