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The samples were obtained during the routine blood monitoring carried out in the National Centre for Sports Medicine over the period of 20092015

Furthermore, this pathway may be beneficial for the rapid regulation of cellular iron homeostasis since the activation of Nrf2 and subsequently HO-1 increases Fe 2+ or because the activation of NCOA4, which induces ferritinophagy to further release Fe 2+ from FTH, seems to be a relatively slow process

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The effect of an adapted digital mental health intervention for sickle cell disease on engagement: a pilot randomized controlled trial