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Competing interests Martin C

Sales of Zyn alone rose in the US by 58.8% between 2019 and 2022, according to one report, and then climbed a further 66% in the third quarter of 2023

The initial clinical sign of cadmium-induced renal lesions is tubular proteinuria, usually detected as increased urinary excretion of low-molecular-weight proteins (such as -2-microglobulin, or alpha-1 macroglobulin) or tubular enzymes such as N -acetyl-/-glucaminidase (NAG)