This approach ensures that solubility measurements are both relevant and representative of real-world screening environments, supporting efficient decision-making in lead optimization
doi: 10.1016/j.gene.2019.143956 115 LimDYJeongYTynerALParkJHY
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Benzodiazepine inverse agonists such as Ro15-4513 have also been shown to be effective in the treatment of HE in animal models of acute [102] or chronic liver failure [103]
