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Clinical therapy of targeting ferroptosis in human diseases Numerous preclinical studies have demonstrated that iron acts as a potent pro-oxidant, contributing to the development and progression of tumors, central nervous system diseases, metabolic diseases, autoimmune diseases, and cardiovascular diseases through the production of highly reactive and cytotoxic free radicals

doi: 10.1016/j.xcrm.2024.101913 122 AlizadehJZekiAAMirzaeiNTewarySRezaei MoghadamAGlogowskaAet al

Sciorio and Smith [77] came to a similar conclusion in their review, adding that further reductions in oxygen may be necessary to achieve excellent blastocyst formation and increase the policy of elective single embryo transfer

Thyroid hormone autoantibodies elicited by diagnostic fine needle biopsy

The discovery of glutathione peroxidase in 1957 established glutathione's role as the body's primary intracellular antioxidant, using selenium-dependent enzymatic reduction of peroxides