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Plasma nicotine analysis was performed by liquid chromatography with tandem mass spectrometry detection (LC-MS-MS) using the instrument in turbo ion spray, positive ion Multiple Reaction Monitoring (MRM) mode

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Nicotine causes blood vessels to become narrow, thereby reducing oxygen flow and nutrients to the skin cells

Thats enough capacity to handle moderate smoke exposurethink a household where someone smokes outdoors but the smell drifts in through windows, or an apartment where a neighbors smoke occasionally infiltrates through shared ventilation

Given that such sampling and testing are already in place to monitor compliance with the VPLPR, there will be no additional costs to Health Canada