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Modern nutritition in health and disease

The mechanism of action of cisplatin (and carboplatin) involves covalent binding to purine DNA bases, which primarily leads to cellular apoptosis

IL-10 modulates lymphocyte reactivity

Thus, the general principle of the selenenylsulfide sensing in the non-reduced TrxR1 is the process of opening selenenylsulfide bond in response to the oxidizing reagents with a highly electrophilic active species