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10.1016/j.redox.2015.01.001 76 TaitI

[130] evaluated the anticancer potential of four binuclear biphenyl organogold(III) complexes, of general formula [(C^C)Au(Cl)(L^L)(Cl)Au(C^C)] (Table 4), across various cellular models

It upregulates the expression of early growth response protein 1 (EGR-1), a transcription factor that controls over 30 downstream genes involved in cytokine production, growth factor signaling, and extracellular matrix remodeling

Aberrant expression of E3 ubiquitin ligases is closely associated with ferroptosis in musculoskeletal diseases (89), with PD-1 playing a regulatory role in this context (90)