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In the 2000s, Donald Sutherland's career in film continued to thrive with roles in the action comedy "Space Cowboys" in 2000, the Civil War drama "Cold Mountain" in 2003, in which he starred in with Nicole Kidman, and the heist film "The Italian Job" in 2003, with Charlize Theron

The tiny, sharp particles become lodged in the lining of the lungs

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THE WAY FORWARD: HIGHLIGHTING INDUSTRY TACTICS TO BUILD ON YOUTH SKEPTICISM TO DISCOURAGE USE After decades of watching its customer base dwindle, the tobacco industry seized on a lax regulatory environment to introduce new products, launched a targeted marketing campaign to draw in youth, introduced flavors to get them to try new products, and delivered high doses of nicotine to keep them coming back for more

At the same time, 16 state legislatures failed to pass proposed cigarette and/or tobacco tax increases