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These changes were accompanied by decreased expression of, peroxisome proliferator-activated receptor gamma genne ( Pparg ), ligand-activated nuclear receptor, which is implicated to regulate fat-specific gene expression and activate adipocyte differentiation

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Universal stated that the initiative would involve the formation of an ALP office within TIMB, ideally in cooperation with government ministries, local farmer unions, and farmer associations.[277] Human Rights Due Diligence in Direct Contracting System Approximately 82 percent of tobacco produced in Zimbabwe in 2016 was sold through direct contracts between buyers and growers.[278] There were 20 companies officially licensed to contract directly with tobacco growers in Zimbabwe in 2017.[279] Human Rights Watch interviewed small-scale farmers who said they had produced and sold tobacco in recent years through direct contracts with several tobacco companies, including Boostafrica, Curverid, Chidziva, Mashonaland Tobacco Company (MTC), NT, Premium,[280] and ZLT

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