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Twenty-five of 57 patients in the safety population experienced a total of 74 treatment-emergent adverse events (TEAEs), including 24 treatment-related adverse events, 6 of which were serious

The compound's dual-agonist mechanism makes it a particularly valuable research tool for studying incretin biology and comparing against single-agonist GLP-1 compounds

Excess adenosine floating around cues the adrenal glands to release adrenaline and cortisol causing increase blood sugar, elevated heart rate, and increased blood pressure

Wong SH, Francis N, Chahal H, Raza K, Salmon M, Scheel-Toellner D, et al

doi: 10.1038/83241