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Dendritic cells located in the epithelium and lamina propria pick up the antigen, which either penetrates the epithelial barrier or is transported by the M cells, and carry it to either the mucosal lymphatic collections or the regional lymph nodes (Buzatu et al

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Importantly, most of the studies with a longitudinal design conducted in Europe have adapted the scale rationale and methods to estimate the level of implementation of tobacco control policies to ensure the temporal comparability and include data about years for which the TCS had not been published 26,27,29,31,32

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