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There are more than 1 10 14 microbial cells in the human intestine, which play important roles in physicochemical and physiological functions via their dynamic interaction with the host, including intestinal development, barrier integrity and function, metabolism, immunity, inflammation, and neurological signaling regulation (Nicholson et al., 2012

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formaldehyde, cadmium and benzene), and nicotine

Additionally, most general surgery operations are performed on internal organs, rather than the skin

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