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Timeline Physical Symptoms Mental & Emotional Symptoms Additional Notes 4-24 hours Cravings, headaches, irritability begin Anxiety may start around day 3 Withdrawal symptoms start quickly and peak early 2-3 days Intense cravings, headaches Mood swings, difficulty concentrating Cravings tend to be strongest within this window 1 week Most physical symptoms reduce Irritability, sleep issues remain Physical symptoms usually lessen significantly 2-4 weeks Symptoms lessen significantly Cravings may persist but weaken Most physical effects resolve by this time 1-3 months Very few physical symptoms remain Anxiety, depression can linger Long-term mental health support may be needed What is the long-term outlook regarding withdrawal and recovery