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Preclinical research has indicated that Withania somnifera elicits antidepressant-like effects that are comparable to those of imipramine and fluoxetine, thereby corroborating its involvement in serotonergic and noradrenergic signaling cascades (78)

Slight redness or irritation at the injection site

F.HuangJ.-F.LloydS

The composition of the sample/lysis buffer also needs to be compatible with the subsequent purification step(s) if the investigator is to avoid time-consuming buffer exchange steps before column chromatography