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At the same time, kidney function also starts to decline even without any disease

Systemic Effects Beyond local reactions, some participants in aod 9604 peptide studies report systemic effects: Mild Headaches : Occurring in approximately 5-8% of research subjects, these typically resolve within hours and may be related to initial adaptation to the peptide

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People with specific gastrointestinal problems, such as Crohns disease or celiac disease, or those who have undergone gastrointestinal surgery may have difficulty absorbing B12 from food and supplements

154,155 Note : In addition to the core approach (B vitamins) described in this section, refer to the Nutrients section later in this Life Extension Protocol for an overview of additional nutritional interventions that may beneficially affect homocysteine metabolism and related pathways