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In brief, the questions related to tobacco cigarette consumption were substituted with EC liquid consumption, based on the results of a large survey of 19,441 vapers

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Voskarides K, Giannopoulou N (2023) The role of TP53 in adaptation and evolution

However, a paucity of knowledge about e-cigarettes or electronic nicotine delivery systems (ENDS) and concerns about their safety and public health impact have raised important concerns about their use

FDA (2018), US Food and Drug Administration, Premarket Tobacco Product Applications and Recordkeeping Requirements. US Food and Drug Administration, Regulation and Enforcement of Non-Tobacco Nicotine (NTN) Products, November 6, 2023, Juul Labs, Juul Labs Statement on FDA Marketing Authorizations, press release, July 17, 2025,