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Table 1 Characteristics of studies included in the meta-analysis and number of participants with precancerous and cancerous lesions, according to tobacco use Table 2 Quality assessment of studies included in the meta-analysis Statistical analysis Systematic review was conducted using Cochrane Program Review Manager Version 5

With the push of a button, or by simply inhaling, the battery heated coils, changing the e-liquid into vapor to deliver nicotine and flavors

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[3] It has been suggested that leukoplakia is an unhelpful term since there is so much inconsistency surrounding its use, [3] and some clinicians now avoid using it at all