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These cells were not able to maintain in vitro normal ATP and 2,3-BPG concentrations

Of interest, eCBs levels did not differ in these two subgroups of patients, indicating that elevations of CSF eCBs are independent of disease duration

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82 Recently, panels of methylation genes, which are more sensitive than single biomarkers, have been reported

5.1 Iron chelators and iron modifiers Iron chelators and modifiers effectively inhibit cellular ferroptosis by regulating the expression and activity of iron transporters and storage proteins, including transferrin and its receptor (TfR1), ceruloplasmin, ferroportin, divalent metal transporter 1 (DMT1), and other membrane iron transport proteins (24, 26)