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These are generally fine in small quantities

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The effects of very large doses can include: an increase in the unpleasant effects feeling faint confusion rapid decrease in blood pressure and breathing rate seizures respiratory arrest (stopping breathing) and death

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The researchers compared two major cigarette brands: Pall Mall, marketed as a discount brand, and Natural American Spirit, a super-premium brand that features a pro-environment marketing campaign - the first-ever corporate social responsibility advertising on cigarette packaging