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The occurrence of ferroptosis in mature erythrocytes has not been confirmed and it seems quite challenging, since ferroptosis studies suffer from the lack of well-established markers and evaluation of this cell death requires a complex approach with identification of typical cellular and subcellular morphological alterations, genetic hallmarks, biochemical changes, expression of certain ferroptosis-related proteins, etc

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Clozapine-related eosinophilia has also occurred in the absence of organ involvement and can resolve without intervention

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The impact on nature of these seemingly insignificant butts is substantial